KEGG   Homo sapiens (human): 27343
Entry
27343             CDS       T01001                                 
Symbol
POLL, BETAN, POLKAPPA
Name
(RefSeq) DNA polymerase lambda
  KO
K03512  DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03410  Base excision repair
hsa03450  Non-homologous end-joining
Network
nt06506  Double-strand break repair
  Element
N01445  Non-homologous end-joining
N01467  V(D)J recombination
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03410 Base excision repair
    27343 (POLL)
   03450 Non-homologous end-joining
    27343 (POLL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    27343 (POLL)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     27343 (POLL)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Other BER factors
     27343 (POLL)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    X-family DNA polymerases
     27343 (POLL)
SSDB
Motif
Pfam: DNA_pol_B_palm DNA_pol_B_thumb DNA_pol_lambd_f HHH_8 HHH_5 NTP_transf_2 BRCT_2 HHH PAG Nore1-SARAH
Other DBs
NCBI-GeneID: 27343
NCBI-ProteinID: NP_001167555
OMIM: 606343
HGNC: 9184
Ensembl: ENSG00000166169
UniProt: Q9UGP5
Structure
Position
10:complement(101578882..101588270)
AA seq 575 aa
MDPRGILKAFPKRQKIHADASSKVLAKIPRREEGEEAEEWLSSLRAHVVRTGIGRARAEL
FEKQIVQHGGQLCPAQGPGVTHIVVDEGMDYERALRLLRLPQLPPGAQLVKSAWLSLCLQ
ERRLVDVAGFSIFIPSRYLDHPQPSKAEQDASIPPGTHEALLQTALSPPPPPTRPVSPPQ
KAKEAPNTQAQPISDDEASDGEETQVSAADLEALISGHYPTSLEGDCEPSPAPAVLDKWV
CAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKSFHKPVTSYQEAC
SIPGIGKRMAEKIIEILESGHLRKLDHISESVPVLELFSNIWGAGTKTAQMWYQQGFRSL
EDIRSQASLTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRR
GKATCGDVDVLITHPDGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLP
GPGRRHRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTAVVRNT
HGCKVGPGRVLPTPTEKDVFRLLGLPYREPAERDW
NT seq 1728 nt   +upstreamnt  +downstreamnt
atggatcccaggggtatcttgaaggcatttcccaagcggcagaaaattcatgctgatgca
tcatcaaaagtacttgcaaagattcctaggagggaagagggagaagaagcagaagagtgg
ctgagctcccttcgggcccatgttgtgcgcactggcattggacgagcccgggcagaactc
tttgagaagcagattgttcagcatggcggccagctatgccctgcccagggcccaggtgtc
actcacattgtggtggatgaaggcatggactatgagcgagccctccgccttctcagacta
ccccagctgcccccgggtgctcagctggtgaagtcagcctggctgagcttgtgccttcag
gagaggaggctggtggatgtagctggattcagcatcttcatccccagtaggtacttggac
catccacagcccagcaaggcagagcaggatgcttctattcctcctggcacccatgaggcc
ctgcttcagacagccctttctcctcctcctcctcccaccaggcctgtgtctcctccccaa
aaggcaaaagaggcaccaaacacccaagcccagcccatctctgatgatgaagccagtgat
ggggaagaaacccaggttagtgcagctgatctggaagccctcatcagtggccactacccc
acctcccttgagggagattgtgagcctagcccagcccctgctgtcctggataagtgggtc
tgtgcacagccctcaagccagaaggcgaccaatcacaacctccatatcacagagaagctg
gaagttctggccaaagcctacagtgttcagggagacaagtggagggccctgggctatgcc
aaggccatcaatgccctcaagagcttccataagcctgtcacctcgtaccaggaggcctgc
agtatccctgggattgggaagcggatggctgagaaaatcatagagatcctggagagcggg
catttgcggaagctggaccatatcagtgagagcgtgcctgtcttggagctcttctccaac
atctggggagctgggaccaagactgcccagatgtggtaccaacagggcttccgaagtctg
gaagacatccgcagccaggcctccctgacaacccagcaggccatcggcctgaagcattac
agtgacttcctggaacgtatgcccagggaggaggctacagagattgagcagacagtccag
aaagcagcccaggcctttaactctgggctgctgtgtgtggcatgtggttcataccgacgg
ggaaaggcgacctgtggtgatgtcgacgtgctcatcactcacccagatggccggtcccac
cggggtatcttcagccgcctccttgacagtcttcggcaggaagggttcctcacagatgac
ttggtgagccaagaggagaatggtcagcaacagaagtacttgggggtgtgccggctccca
gggccagggcggcggcaccggcgcctggacatcatcgtggtgccctatagcgagtttgcc
tgtgccctgctctacttcaccggctctgcacacttcaaccgctccatgcgagccctggcc
aaaaccaagggcatgagtctgtcagaacatgccctcagcactgctgtggtccggaacacc
catggctgcaaggtggggcctggccgagtgctgcccactcccactgagaaggatgtcttc
aggctcttaggcctcccctaccgagaacctgctgagcgggactggtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Network (3)   
   KEGG NETWORK (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (79)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PRONIT (58)   
Protein sequence (68)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (66)   
DNA sequence (119)   
   RefSeq(nuc) (67)   
   GenBank (26)   
   EMBL (26)   
3D Structure (86)   
   PDB (86)   
Protein domain (10)   
   Pfam (10)   
All databases (373)   

Download RDF
DBGET integrated database retrieval system